Abstract

Shruti Pandey*, Dr. Atul Khajaria* and Dr. Raj Kumar*

ABSTRACT

Wound infections are a significant global health concern, often caused by bacterial pathogens such as Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. The rising prevalence of antibiotic resistance has made the treatment of these infections increasingly challenging, necessitating the exploration of alternative therapeutic agents. Citrus sinensis (sweet orange), widely recognized for its nutritional and economic value, has gained attention for its antibacterial properties derived from its rich phytochemical composition, including flavonoids, phenolic acids, and essential oils. Various extracts of Citrus sinensis, including peel, juice, and essential oil, have demonstrated significant antibacterial activity against both Gram-positive and Gram-negative bacteria isolated from wound infections. Additionally, synergistic effects have been observed when Citrus sinensis extracts are combined with conventional antibiotics, enhancing their antibacterial potency. This review highlights the antibacterial potential of Citrus sinensis and emphasizes its role as a sustainable and natural therapeutic agent in combating bacterial wound infections.