Abstract

*M. Figuigui, J. Hammani, A. Lamine, M. Lahlali, H. Abid, N. Lahmidani, M. EL Yousfi, M.EL Abkari, A. Ibrahimi and D. Benajah

ABSTRACT

Sarcoidosis is a multisystemic inflammatory disease of indeterminate etiology characterized in histology by the presence of non-caseating granulomas. The mediastino-pulmonary localization is the most frequently found, the other extra-thoracic locations including digestive are rarely encountered. Through an observation we present a very rare extra-pulmonary manifestation of sarcoidosis that of pancreatic sarcoidosis This is a young 47-year-old female patient with a history of antibacillary treatment for microscopic tuberculosis (TB) in 1986, who presented to the emergency department in an angiocholitis panel and whose imaging had suspected sarcoidosis due to double mediastino-pulmonary and pancreatic localization The diagnosis was retained histologically by the revelation of an epithelioid and gigantocellular granuloma without caseous necrosis Treatment is based essentially on systemic corticosteroid therapy 0.5 mg per kg per day with good clinical progress. Pancreatic involvement during sarcoidosis is very rare, and usually with favorable prognosis on corticosteroid treatment.