World Journal of Pharmaceutical
and Medical Research

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An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
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Abstract

CLINICAL STUDY OF DASHANG LEPA IN VRANASHOPHA (ACUTE INFLAMMATORY SWELLINGS)

Dr. Kumar Ravindra* and Dr. Gupta S. J.

ABSTRACT

Background/Purpose: Vrana and Vranashopha have been a topic of interest for the surgeons since ancient times. Vranashopha occurs either as a result of vitiated doshas or may be of traumatic origin. This has been emphasized in classics of Ayurveda in various contexts. The father of surgery Acharya Shushruta has explained the Vranashopha as: swelling like a thick, elevated mass, even or uneven, residing in the skin and muscles, having accumulation of the doshas and arising in any one part of the body (localised). It is entirely different from other swellings like granthi (tumour), vidradhi (abscess), alaji (a kind of skin disease) and such other disease of many shapes. As per symptomatology Vranashopha is very close to surface inflammatory swelling. Inflammatory swellings such as – cellulitis, erysipelas, boil, carbuncle etc. are major issue in health sciences. Methods: Dashang Lepa contains 10 commonly and easily available and very cost affective indigenous drug which all having good effect in reducing the Vranashopha. For the clinical study, 20 patients of inflammatory swelling after detail clinical history and investigatory findings as per designed proforma, were registered from OPD/IPD of the Department of Shalya Tantra, Sir Sunderlal hospital I.M.S. B.H.U. Varanasi (U.P.). Patients were divided in two groups (IA & IB) based on Total Leukocyte Count [TLC]. Results: Total percentage reliefs in sign and symptom of inflammatory swellings in 20 patients. The data reveals relief in pain was 77.77% and 100% in Group IA and IB respectively. Relief in oedema (swelling) was 66.66% and 90.00% in Group IA and IB respectively. Relief in tenderness was 75.00% and 83.33% in Group IA and IB respectively. Relief in erythema was 83.33% and 91.66% in Group IA and IB respectively. Relief in fever was 100% in both Groups respectively. Conclusion: The present study showed that the trial drug (Dashang Lepa) possessed significant effect against acute inflammation in comparison to standard group (Sumag).

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