Abstract

Dr. Yasir Hakim*, Adam Daoud Abakar, Hagir Gubara EL-shik Ahmed, Basma Abbas, Asad Adam, Abuelgasim Mohammed Ahmed

ABSTRACT

Background: Primary infections caused by Toxoplasma gondii can lead to serious complications in pregnant women. The aim of this study was to determine the Seroprevalence of T. gondii and Rubella virus among pregnant women in EI-Hasahiesa Teaching Hospital and to evaluate the use of outcomes for the prevention of congenital rubella syndrome and congenital toxoplasmosis. Material and Methods: Data were obtained from sera collected from eighty of pregnant women; during their visit to Maternity Hospital, between May-August 2016. Serological analysis for latent toxoplasmosis and Rubella virus levels of (IgG) and active toxoplasmosis and Rubella (IgM) was done using Immunochromatography test and Electro Chemiluminescence Immuno Assay. Results: The specific IgG antibodies were found to be positive in 2cases (2.5%) for toxoplasmosis and none of the examined women had IgM toxoplasma antibodies and the examined women had IgG anti Rubella antibodies(1.2%) and (0%) for IgM antibodies. The rate of infection was detected among women aged between (15 – 25)years for Rubella virus and(26-35) years for Toxoplasma. Rubella vaccination programs during childhood and preconceptional periods rather than antenatal screening appear to be more efficient for eliminating congenital rubella syndrome. In this study showed that, there were high percentages of negative T. gondii & Rubella antibodies in pregnant women and suggests that the prevention of congenital rubella syndrome can be achieved through efficient vaccination programs. Conclusion: The study revealed that, there were high percentages of negative T. gondii Rubella antibodies in pregnant women.