World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
IMPACT FACTOR: 7.533

ICV : 78.6

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Abstract

A RANDOMIZED OPEN LABELLED COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF AGNIKARMA WITH PANCHDHATU SHALAKA AND CHANDRODAYA VARTI IN THE MANAGEMENT OF KARNINI YONIVYAPAD W.S.R. CERVICAL EROSION

*Dr. Sunita Kumari, Prof. Dr. Jitesh Kumar Panda, Prof. Dr. Suniti

ABSTRACT

Cervical erosion is one of the most common gynecological conditions encountered in reproductive-aged women. It is characterized by the replacement of squamous epithelium of the ectocervix by columnar epithelium and may present with symptoms such as vaginal discharge, itching, contact bleeding, dyspareunia, and discomfort. Although benign in nature, untreated cervical erosion may predispose to chronic cervical pathology and requires timely management. In Ayurveda, cervical erosion can be correlated with Karnini Yonivyapad and Garbhashaya Grivamukhagata Vrana based on its symptomatology and pathogenesis. Conventional treatments such as cauterization, cryotherapy, and laser therapy may be associated with recurrence and adverse effects. Therefore, there is a need for a safe, effective, and economical treatment modality. Agnikarma is a well-established para-surgical procedure in Ayurveda and has shown promising results in managing cervical lesions. The present study is planned to evaluate the efficacy of Agnikarma with Panchdhatu Shalaka and Chandrodaya Varti in the management of Karnini Yonivyapad w.s.r. Cervical Erosion. A randomized open-labelled comparative clinical study will be conducted on 70 patients, divided equally into two groups of 35 patients each. Group A will receive Agnikarma with Panchdhatu Shalaka and Group B will receive Chandrodaya Varti. The study aims to provide scientific evidence regarding the comparative efficacy of these interventions and establish an effective Ayurvedic management protocol for Cervical Erosion. Methodology: 70 patients of Karnini Yonivyapad will be selected on the basis of inclusion and exclusion criteria. All patients will be divided into two groups. Each group having 35 patients. In group A patients will be receiving single sitting of Agnikarma with Panchdhatu Shalaka and in group B patients will be receiving single sitting of Agnikarma with Chandrodaya Varti after cessation of menses.Observations will be done on the basis of before, and after subjective and objective parameters.

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