World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
IMPACT FACTOR: 7.533

ICV : 78.6

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Abstract

COMPARATIVE PHARMACEUTICAL PREPARATION OF KUSHTHARAKSHASA TAILA PREPARED WITH AND WITHOUT WATER: A PHARMACEUTICAL STUDY

Dr. Yashwant Singh Sengar*, Dr. Sangeeta Rao, Dr. Vikram S., Dr. Rubina B.S.

ABSTRACT

Background: Kushtharakshasa Taila is a classical Ayurvedic formulation described in Bhaishajya Ratnavali and indicated in various Kushta (skin disorders). The formulation contains several purified mineral drugs along with herbal ingredients processed in Sarshapa Taila. Classical references provide different approaches for its preparation, including formulations prepared with and without addition of water. Scientific documentation of these pharmaceutical procedures is essential for standardization and reproducibility.[1] Aim: To prepare Kushtharakshasa Taila with and without water according to classical principles and compare their pharmaceutical characteristics, observations, and yield. Materials and Methods: Purification of Parada, Gandhaka, Haratala, Manashila, and Tamra was carried out according to classical Rasashastra procedures. Tamra Bhasma was prepared through Shodhana, Marana, and Amritikarana. Kajjali was prepared using equal quantities of Shuddha Parada and Shuddha Gandhaka. Herbal ingredients including Kushta, Saptaparna Twak, Chitraka Moola, Bakuchi, Aragwadha, and Rasona were powdered and incorporated into the formulation. Two samples of Kushtharakshasa Taila were prepared: Sample I without water and Sample II with water (1:4 proportion of Taila and Jala). Both samples were subjected to Surya Paka under identical conditions and evaluated organoleptically. Results: Sample I (without water) yielded 374 mL (48%) of Taila, whereas Sample II (with water) yielded 342 mL (44%). Sample I showed earlier development of characteristic odour, froth formation, and colour change compared to Sample II. The final product of Sample I appeared greenish-black, while Sample II exhibited a reddish-brown to dark-brown colour. Conclusion: Preparation without water demonstrated comparatively faster processing and higher yield than preparation with water. Distinct differences in colour, odour development, and pharmaceutical characteristics were observed between the two samples.

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