CARDIAC BIOMARKERS
Seema D. Jogad*, Megha S. Bora, Sayali S. Shelar, Madhuri S. Harde
ABSTRACT
Cardiovascular diseases are important factor to cause mortality and disability globally. High blood pressure, hyperglycemia, smoking and hpercholestremia are responsible to cause cardiovascular disease. Cardiac biomarkers are specific substances released from the heart muscles when it is get damaged as a result of myocardial infraction. Biomarkers are use to identify the presence, reasons and extent of damage of cardiac tissue, they enhances the risk stratification measurement for cardiovascular disease. Various biomarkers are explained in this review with their roles, troponin are the current standard for diagnosis of myocardial infraction, pregnancy associated plasma proteins-A (PAPP-A) is a capable biomarker for risk identification in cardiac stress, matrix metalloproteinase are responsible for plague repture, it is estimated that myloperoxidase ismain contributor within the development and rupture of plague, H-FABP, soluble suppression of tumorigenicity an miRNA has probable to improve diagnosis and treatment of patients suspect of an adverse cardiac events, MR-proADM is important marker for the patient who have atherosclerotic plague, heart failure and cardiovascular disease.
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