Abstract

*Priya Pankaj Wakchaure, Priyanka Jalindar Kaitake, Mahesh Gokul Shinde, Ajay S. Mule

ABSTRACT

Skin-related fungal diseases rank among frequent dermatological problems and impact many people across the globe. Because they are considered safer, easier to obtain, and less likely to cause unwanted reactions, plant-based remedies are being chosen more often. This research centers on designing and assessing a multi-herb antifungal cream made sing leaf-derived extracts from Catharanthus roseus (Sadaphuli) together with Pongamia pinnata (Karanja). An oil-in-water emulsion served as the base, incorporating beeswax, liquid paraffin, glycerine, borax, methyl paraben, and peppermint oil. The finished product was examined for sensory attributes, acidity/alkalinity level, ease of spreading, ease of removal with water, potential to irritate, and additional physicochemical measures. Overall, the formulated cream demonstrated adequate physical qualities, a skin-appropriate pH range, and smooth application with good spread. Throughout testing, irritation was not detected. These results indicate the prepared polyherbal cream could be considered a promising antifungal product for topical use.