World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
IMPACT FACTOR: 7.533

ICV : 78.6

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SJIF Impact Factor: 7.533

Abstract

VARIATIONS IN CIRCLE OF WILLIS AND THEIR CLINICAL IMPLICATIONS: A COMPREHENSIVE ANATOMICAL STUDY

*1Dr. Dhara V. Patel (MD Rachana Sharira), 2Dr. Archana A. Patel (MD Rachana Sharira)

ABSTRACT

Background: The Circle of Willis (CoW) is a crucial arterial anastomotic network at the base of the brain that ensures collateral circulation. However, anatomical variations are common and may influence cerebrovascular diseases. Objective: To study anatomical variations of the Circle of Willis and evaluate their clinical implications. Methods: A descriptive study using cadaveric specimens and radiological imaging was conducted. Variations were classified based on completeness and arterial anomalies. Results: A complete Circle of Willis was observed in fewer cases, while most showed variations such as hypoplasia and aplasia. Conclusion: Variations are common and clinically significant in cerebrovascular disorders.

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