World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
IMPACT FACTOR: 7.533

ICV : 78.6

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Abstract

INTEGRATED PHYTOCHEMICAL PROFILING AND ANALYTICAL CHARACTERIZATION OF CORDIA DICHOTOMA G. FORST LEAVES USING SPECTROSCOPIC AND CHROMATOGRAPHIC TECHNIQUES

Ittagi Shanmukha*, Suhas R. M., C. M. Manu, Vinuth Chikkmath

ABSTRACT

Medicinal plants continue to serve as a vital source of bioactive compounds with significant therapeutic potential. The present study aims to systematically evaluate the phytochemical composition of Cordia dichotoma G. Forst. leaves through integrated analytical approaches. Preliminary phytochemical screening revealed the presence of major secondary metabolites including alkaloids, flavonoids, tannins, glycosides, and phenolic compounds across different solvent extracts. Quantitative estimation demonstrated that the hydroalcoholic extract possesses a high concentration of total phenolics (96.4 mg CE/g), flavonoids (99.2 mg QE/g), and tannins (163.1 mg TAE/g), indicating strong antioxidant potential.[1,2] FTIR spectral analysis confirmed the presence of functional groups such as hydroxyl, aromatic, and glycosidic linkages, supporting the occurrence of phenolic and flavonoid compounds. HPLC chromatographic profiling revealed a prominent peak at retention time 2.633 min, suggesting the presence of major phenolic constituents. These findings were consistent with reported literature emphasizing the phytochemical richness and pharmacological relevance of Cordia dichotoma leaves.[3-5] Overall, the study provides comprehensive analytical validation of bioactive constituents, highlighting the plant’s potential as a natural source for pharmacological and therapeutic applications.

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