World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
IMPACT FACTOR: 7.533

ICV : 78.6

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Abstract

PHYTOPHARMACOLOGICAL INVESTIGATION AND FORMULATION OF TRADESCANTIA SPATHACEA DROPS FOR OTALGIA MANAGEMENT

Sakshi Choudhari*, Shobhit Kishor Suralke

ABSTRACT

Otalgia (ear pain) is a common condition caused by infection or inflammation of the ear. Although conventional treatments such as analgesics and antibiotics are widely used, prolonged use may lead to side effects and antimicrobial resistance. Tradescantia spathacea is a medicinal plant known for its anti-inflammatory, antimicrobial, and antioxidant properties, making it a potential natural remedy. The present study focuses on the phytopharmacological investigation and formulation of herbal ear drops using Tradescantia spathacea for otalgia management. The plant material was collected, authenticated, and extracted, followed by preliminary phytochemical screening to identify bioactive compounds such as flavonoids, tannins, phenolics, saponins, and alkaloids. The extract was formulated into herbal ear drops using glycerin and propylene glycol as vehicles. The formulation was evaluated for physicochemical parameters including pH, viscosity, appearance, homogeneity, and stability. Results showed that the formulation possessed acceptable characteristics and remained stable during the study. The study suggests that Tradescantia spathacea based herbal ear drops may serve as a promising natural alternative for the management of otalgia.

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