Abstract

Dr. Minal Mahendra Kamble*

ABSTRACT

In Ayurveda the pharmaceutical outcome of a drug product is achieved through the proper application of Agni, Kala and Paatra. These guidelines are keys to producing quality formulations and are critical for Bhaishjyakalpana. Agni will be used for the conversion, concentration and activation of the active components during the preparation processes, such as Sneha Kalpana and Avaleha. Correct regulation of Agni will optimize the extraction of active components, prevent the damage or decomposition of the active components, and improve bioavailability. Effective regulation of Kala will control how long products are prepared, when to prepare them, at which time of year to prepare them, and when to administer them following completion of the preparation process, and will ultimately regulate the Veerya and stability. The choice of a product's Paatra such as Loha and Tamra may also influence the chemical reactions among the ingredients and distribution of heat during preparation. The use of Agni, Kala and Paatra in combination will create Samskara which improves safety, stability and effectiveness of formulations.