World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

MANAGEMENT OF EKAKUSTHA (PLAQUE PSORIASIS) THROUGH INTEGRATED SHODHANA AND SHAMANA CHIKITSA: A SINGLE CASE STUDY

Dr. Subham Pradhan, Dr. Swetanjali Behera, Dr. Soumya Ranjan Das, Dr. Jitendra Samal*, Dr. Lijina Swain

ABSTRACT

Background: Ekakustha, characterized by aswedana (absent sweating), mahavastu (large lesions), and matsya-shakalopama (fish-scale appearance), correlates with plaque psoriasis. Classical Shodhana-Shamana remains underexplored in modern clinical practice. Objective: Evaluate integrated Shodhana-Shamana protocol efficacy in treatment-resistant Ekakustha. Case Presentation: A 33-year-old male with 12-month widespread psoriasis resistant to antihistamines, steroids, and vitamin D analogues presented with bilateral erythematous plaques, severe pruritus, and alopecia. Treatment: Nidana parivarjana, Deepana-Pachana (Days 1-3), Snehapana with Mahatiktaka Ghrita (Days 4-8), Abhyanga-Swedana with Dashamoola (Days 8-10), Virechana with Trivrit-Triphala (Day 11), followed by 30-day Shamana with Potala Katuruhinyadi Kashaya, Arogyavardhini Vati, Dusivishari Gutika, Gandhaka Rasayana, and topical Brihat Dantapala Taila. Results: Psoriasis Area and Severity Index (PASI) score declined from severe (>20) to absent (0) at Day 45. Complete resolution of erythema, induration, scaling, and pruritus with significant hair regrowth. No relapse at follow-up. Conclusion: Integrated Shodhana-Shamana chikitsa effectively addresses Samprapti through sequential Ama pachana, Kleda soshana, and Raktashodhana, providing sustainable Ekakustha management. Multicentric trials recommended.

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