CONTEMPORARY WEIGHT LOSS MEDICATIONS: “A COMPREHENSIVE REVIEW ON THE THERAPEUTIC EFFICACY, SAFETY AND ADVERSE EFFECTS.”
Vyas Prakruti, Patel Harsh P., Dr. Manan Sharma, Dr. Anjali Gupta, Dr. Akshat Parashar
ABSTRACT
This article critically evaluates and understands the weight loss medications or anti obesity medicines to apprise the modern and traditional medication’s safety, efficacy and the side effects or ADRs. An excessive build up of body fat is the hallmark of obesity, which is a long term metabolic disorder that can have a detrimental impact on a person's body and increase their risk of developing certain chronic illnesses. This can be determined by examining the Body Mass Index (BMI ), which normally equals 30 kg/m 2 , according to the World Health Organization (WHO). Around the world, about 2 billion people are obese. Some unpredictable lifestyle changes, such as sleeping too little, consuming too many calories, and taking medications with weight gaining side effects, can cause it. To address this problem, a few pharmacological agents or biologically active drugs have been approved by the United state food and drug administration (USFDA) and European medicines agency (EMA). Among these drugs are Orlistat, Phentermine/Topiramate, Lorcaserin, Naltrexone/Bupropion, and L iraglutide. Constipation and nausea are both possible side effects of these medications. One of the natural substances used to reduce weight is Curcumin. through a combination of medication, moderate physical activity, and dietary modifications. The side e ffects of all these medications can be decreased once treatment is discontinued.
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