World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
IMPACT FACTOR: 7.533

ICV : 78.6

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Abstract

MULTIPLE EMULSIONS OBTAINED BY A ONE-STEP METHOD - NIACINAMIDE RELEASE ASSAY

Rocha-Filho P.A.*, Spineli K.A.S.

ABSTRACT

Multiple emulsions (ME) are used as alternatives in skin care products due to particular properties as: (a) ability to encapsulate cosmetics; (b) protection of the encapsulated substance from the oxidation process; (c) ability to encapsulate incompatible substances; (d) sustained release. Their use in cosmetics depends on the components of the formulation, parameters of the preparation process and studies release of the active in a safe and efficient way. ME cosmetic containing niacinamide was prepared by the one-step method and indicated for the protection against skin ageing. It was employed vegan surfactants and as oily phase the avocado oil and the sunflower oil. The niacinamide was used as active for studies of in vitro liberation. Multiple emulsions were developed by one step method by phase inversion using avocado or sunflower oils, which have antioxidant properties. It can be observed that niacinamide was encapsulated and released slowly from the W/O/W emulsions.

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