World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

PHARMACEUTICAL AND THERAPEUTIC REVIEW OF PANCHAMULADI GHRITA – AN AYURVEDIC AND MODERN PERSPECTIVE

Dr. Kaustubh Badave*, Dr. Kavita Deshmukh, Dr. Kalyani Jadhav

ABSTRACT

Gh?ita Kalpana (medicated ghee preparations) represent one of the most significant dosage forms in Ayurveda. Among these, Panchamuladi Gh?ita is traditionally used in the management of Graha?i Roga and Vata-kaphaj disorders. This review aims to analyze the pharmaceutical aspects, classical references, and modern pharmacological relevance of Panchamuladi ghrita. The formulation, composed of Panchmula (Bilva, Agnimantha, Shyonaka, Patala, Gambhari) along with Haritaki, Vyosha, Pippalimula, Saindhava, and other digestive and anti-inflammatory herbs, processed in ghee with acidic media such as Sukta or Matulunga swaras, exhibits deep intestinal action. Modern evidence suggests that ghee-based Ayurvedic formulations enhance drug bioavailability and have mucosal healing potential. The present review concludes that Panchamuladi Ghrita is a potent Ayurvedic preparation for gastrointestinal disorders with promising scope for further pharmacological and clinical research.

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