World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
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Abstract

INTEGRATED MANAGEMENT OF DIGITAL GANGRENE IN A DIABETIC ELDERLY PATIENT: A CASE REPORT

Murali Krishna S., Gopi Krishna B. J.

ABSTRACT

Diabetic foot ulcers and digital gangrene are severe complications affecting 6 10% of diabetic patients worldwide, particularly elderly individuals with poor glycem ic control, leading to limb loss, reduced quality of life, and substantial healthcare costs. This case report describes the integrated management of digital gangrene in a 70 year old male with Type II Diabetes Mellitus (HbA1c 8.0%) presenting with a 15 day nonhealing wound on the left fourth toe that turned black, accompanied by pain, bilateral lower limb discoloration, edema, constipation, and depression. Diagnosis was confirmed via clinical findings (swelling, redness, tenderness), labs (FBS 108 116.9 mg/ dl, PPBS 175.6 mg/dl), and peripheral angiogram showing arterial stenoses/occlusions. Treatment combined modern medicine IV Durataz 4.5g, Pantoprazole 40mg, Tramadol, Sitagliptin+Metformin, Ecosprin 150mg, Clopilet 75mg, Linezolid 600mg (13 04 2025 to 01 0 5 2025) with minor distal phalanx amputation on 01 05 2025 without local anesthesia. Ayurvedic interventions included Manjistadi Kshara Basti (Sukumara Ghrita 80ml Anuvasana, Manjistadi Ksharakashaya 300ml Niruha), Kseerabala Taila Pichu, Matra Basti (Panc hagavya Ghrita), Jatyadi Taila dressings, and internals (Meha Abhaya, Maha Manjishtadi, Punarnavastaka Kashayas; Nimbadi Guggulu). Post treatment, pain/inflammation subsided, wound granulated steadily, edema resolved, mood improved, and mobility was regain ed by discharge. Modern therapies controlled the infection, glycemia and circulation; Ayurveda aided detoxification, vata pacification, and regeneration. This synergistic approach highlights potential for limb salvage in diabetic gangrene, warranting furth er research on standardized integrative protocols.

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