World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

COMORBIDITY OF NEUROPATHY OF MEDIAN AND ULNAR NERVES IN PARKINSON’S DISEASE PATIENTS

Dr. Osama Abdel-Salam*, Zakaria M. Ahmed and Mohamed Abdel-Moneim

ABSTRACT

Objective: The aim of this article is to find the neuropathy of ulnar and median nerves in Parkinson’s disease patient. Subjects: Fifty subjects were enrolled in this study. They were classified into group (I): 25 patients had Parkinson’s disease and group (II) constitutes 25 normal healthy individuals used as controls. Methods: All patients and control subjects were subjected to electrophysiology parameters of median and ulnar nerves that were recorded and statistically compared. Results: According to electrophysiology, we confirmed median neuropathy in 8 patients (16.0%); bilateral in 5 patients and unilateral in 3 patients and ulnar neuropathy in 4 patients (8.0%) of the PD group. While mean age (???? = 0.0021), age at PD onset (???? = 0.0081), and H&Y scores (???? = 0.0122) were significant, tremor and rigidity scores were not. Conclusion: Medial and ulnar neuropathy was observed in PD patients and a disease related peripheral neurodegeneration beyond symptom severity occurs.

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