Abstract

Dr. Isuwarya Bharany S.*, Dr. Saran Babu, Dr. Vikram S., Dr. Malavika V. S., Dr. Sorubini Loganathan

ABSTRACT

The concept of Yougika Dravya Siddhanta forms the foundation of compound formulations in Ayurveda, emphasizing the synergistic and antagonistic interactions between multiple ingredients to achieve enhanced therapeutic efficacy. Unlike Eka Mulika Dravya (single-drug formulations), Yougika Dravya involves the thoughtful combination of two or more substances - herbal or mineral - guided by classical parameters such as Rasa, Guna, Veerya, Vipaka, and Prabhava. This article explores the comprehensive principles governing the formulation, including the stages of preparation (Dravya Sangrahana, Samskara and Prayoga) and highlights the significance of Tridosha and Panchamahabhuta Siddhanta, Viruddha Ahara, and the role of Prakshepaka Dravyas in optimizing bioavailability and palatability. Through proper understanding and systematic application of these concepts, Yougika Dravya Siddhanta underscores the holistic philosophy of Ayurveda - where the Guna-Karma of a medicine emerges from the combination of its constituents rather than their individual effects. A clear understanding of these Siddhantas ensures correct interpretation of Vyadhi condition and helps pharmaceutically as well as therapeutically in maintaining quality, safety and potency of the Aushada.