Abstract

Dr. B. Mazharunnisa*, Dr. N. S. Kareemunnisa

ABSTRACT

Infertility (Uqr), particularly due to Polycystic Ovarian Disease (PCOD) or Marz-e-Akyas e khusytar Rehem, is one of the leading causes of anovulatory infertility among women of reproductive age. It is characterized by menstrual irregularities, obesity, hirsutism, and hormonal imbalance, resulting in ovulatory dysfunction. The present clinical study was conducted to evaluate the efficacy of Unani formulations in the management of infertility caused by PCOD. Group A: Received a combination of Ustukhuddoos (Lavandula stoechas), Gaouzaban (Borago officinalis), Gule-Tisu (Butea monosperma), Musli Safed (Chlorophytum borivilianum), and Musli Siyah (Curculigo orchioides). Group B: Received Aftimoon (Cuscuta reflexa), Afsanteen (Artemisia absinthium), Sadab Khushk (Ruta chalepensis), Khulanjan (Alpinia galanga), Bozidan (Tanacetum umbelliferum), and Asgandh Nagori (Withania somnifera). The formulations were administered in powdered and decoction forms from the 1st to 25th day of the menstrual cycle for three consecutive months. Clinical evaluation, hormonal assays, and ultrasonography (USG) were performed to assess ovulation and symptomatic improvement. The Unani formulations used in this study were effective in restoring menstrual regularity and inducing ovulation in patients with infertility due to PCOD. The combination of Unani herbs possessing emmenagogue, deobstruent, anti-inflammatory, aphrodisiac, and insulin-sensitizing properties proved beneficial in correcting hormonal imbalance and improving reproductive function. These findings substantiate the classical Unani concept that Sue Mizaj Barid Balghami (cold and phlegmatic temperament) and humoral imbalance contribute to anovulatory infertility.