World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

CLINICAL EVALUATION OF TALPATRI GHRITA IN DUSHTA VRANA: A RANDOMIZED CONTROLLED STUDY

Dr. Mayank Pratap Singh*, Dr. R. C. Yakkundi, Dr. Sachin Patil, Dr. Akshay Ganachari

ABSTRACT

Background: Dushta Vrana (chronic non-healing wounds) remains a major challenge in surgical practice, characterised by slough, pain, discharge, foul odour and delayed healing. Ayurveda describes numerous formulations with Vrana Shodhana and Ropana properties.[1] Talpatri Ghrita, prepared from Talpatri (Borassus flabellifer) and Ghrita, has been traditionally indicated for wound management.[2,3] Aim: To evaluate the clinical efficacy of Talpatri Ghrita in the management of Dushta Vrana. Materials and Methods: A randomised controlled clinical study was conducted on 40 patients diagnosed with Dushta Vrana. Patients were randomly divided into two groups: Group A – Local application of Talpatri Ghrita; Group B – Povidone-Iodine dressing (control). Assessment was done on the basis of pain, discharge, wound size and granulation tissue formation on days 0, 7, 14 and 21. Results: Group A showed significantly faster reduction in discharge and wound area, earlier granulation tissue formation and greater pain relief compared to Group B (p < 0.01). Conclusion: Talpatri Ghrita demonstrated potent Vrana Shodhana and Ropana effects, offering a safe and cost-effective Ayurvedic alternative to conventional antiseptic dressings in the management of Dushta Vrana.

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