World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
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ICV : 78.6

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Abstract

THERAPEUTIC INSIGHTS INTO MADHU MISHRITA JATIPATRADI KWATHA GANDUSHA IN MUKHAPAKA (ORAL ULCERS): A CRITICAL REVIEW

Dr. Swati Chauhan, Dr. Shaweta, Dr. Ankita, Dr. Rashmi Bisht

ABSTRACT

Mukhapaka is frequently encountered oral disorder described in Ayurveda, characterized by painful ulcers, burning sensation and difficulty in mastication and swallowing. In modern science, it can be correlated with recurrent aphthous stomatitis (Oral ulcers), a condition with multifactorial etiology such as nutritional deficiencies, stress, trauma, hormonal balance, and immune dysfunction. Despite its common occurrence, conventional management remains symptomatic, offering only temporary relief without preventing recurrence. Ayurveda provides holistic and sustainable solutions for oral health through local and systemic approaches. Among the local measures, Gandusha (therapeutic gargle) is highlighted as both preventive and curative. Madhu Mishrita Jatipatradi Kwatha Gandusha is particularly effective in Mukhapaka, combining the anti-inflammatory, antimicrobial, antioxidant, and wound healing effects of Jatipatradi Kwatha with the soothing, healing and Yogavahi properties of Honey (Madhu). This critical review aims to analyze the therapeutic role of Madhu Mishrita Jatipatradi Kwatha Gandusha in the management of Mukhapaka. Classical references, Pharmacological actions of ingredients, and modern scientific evidence are discussed. The review suggests that this Gandusha alleviates pain and burning sensation, accelerates ulcer healing, prevents secondary infection, and improves oral hygiene. Being safe, economical, and easy to practice, it offers significant clinical value in recurrent oral ulcers. Further large-scale clinical studies are warranted to establish it as an evidence-based therapy.

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