World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

EVALUATION OF EFFECT OF INJECTABLE PLATELET RICH FIBRIN ON THE ALKALIZING ACTIVITY AND ION RELEASE OF MINERAL TRIOXIDE AGGREGATE AND BIODENTINE – AN IN VITRO STUDY

*Dr. Nutan Kumari, Dr. Ananthakrishna S., Dr. Pradeep P. R., Dr. Aishwarya G. Bhattad and Dr. Juned Ahmed Choudhury

ABSTRACT

Aim: To assess the influence of iPRF on the pH and Ca2+ ion release from MTA and Biodentine. Material and Methods: Cylindrical samples were prepared of MTA control, MTA mixed with iPRF, BD control and BD mixed with iPRF. After an initial set, the samples were placed in falcon tubes containing 10ml deionized water. This solution was checked for pH followed by Ca2+ ion release at intervals of 3h, 24h, 14 days and 28 days. Results: pH analysis revealed no significant differences between the tested groups, all groups exhibited alkaline pH. Ca2+ion analysis revealed highest release for BD control followed by BD mixed with IPRF. MTA mixed with iPRF reported higher Ca2+ ion release compared to MTA control. Conclusions: iPRF did not significantly influence the pH of MTA and Biodentine. Addition of iPRF increased the Ca2+ ion release from MTA, while it had no significant difference on the Ca2+ion release of Biodentine at the end of 28 days.

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