Abstract

Moulika P.*, Bhargavi V., Nagini T., Nithisha Ch, Sravani V., Sahithyareddy

ABSTRACT

ABSTRACT Ethosomes are cutting-edge nanocarriers made to effectively transfer active anti-aging and medicinal ingredients via the skin. While ethosomal systems are conceptually complex, they are simple to prepare, secure to use, and can be combined to greatly increase their utility. These innovative lipid-based vesicles, which are soft and flexible, are made mostly of phospholipids, ethanol, and water. These components give them special properties, such as increased skin permeability and deformability and the capacity to penetrate the stratum corneum and deliver active pharmaceutical ingredients. By rupturing the stratum corneum's lipid bilayer, ethanol allows active substances to penetrate deeper. Ethosomes have increased drug-loading capacity, enhanced bioavailability, and the ability to hold to encapsulate both Water-soluble and lipid-soluble molecules, in contrast to traditional liposomes. They are a viable platform for non-invasive therapeutic solutions because of their prospective uses in cosmeceuticals, transdermal medication administration, and the treatment of different skin conditions. Drugs, peptides, and macromolecules that are hydrophilic or lipophilic can be delivered using ethersomes with exceptional efficiency.