A BEAUTIFUL BETRAYAL: WHEN COLLAGEN BECOMES THE ENEMY
Mohammed Shanil P.*, Farsana Jasmin K.
ABSTRACT
Background: Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease characterized by skin fibrosis, vasculopathy, and internal organ involvement. Early recognition is critical due to potentially life-threatening complications. Case Presentation: We report a 33-year-old female presenting with rapidly progressive skin thickening, Raynaud’s phenomenon, and new-onset exertional dyspnea. Serology revealed anti-Scl-70 positivity. High-resolution CT (HRCT) of the chest showed early interstitial lung disease (ILD). Treatment and Outcome: The patient was managed with immunosuppressive therapy including mycophenolate mofetil and low-dose corticosteroids, showing stabilization of lung function and cutaneous symptoms over 6 months. Conclusion: This case highlights the importance of prompt diagnosis and early treatment initiation in systemic sclerosis to prevent irreversible organ damage.
[Full Text Article] [Download Certificate]