World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

A BEAUTIFUL BETRAYAL: WHEN COLLAGEN BECOMES THE ENEMY

Mohammed Shanil P.*, Farsana Jasmin K.

ABSTRACT

Background: Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease characterized by skin fibrosis, vasculopathy, and internal organ involvement. Early recognition is critical due to potentially life-threatening complications. Case Presentation: We report a 33-year-old female presenting with rapidly progressive skin thickening, Raynaud’s phenomenon, and new-onset exertional dyspnea. Serology revealed anti-Scl-70 positivity. High-resolution CT (HRCT) of the chest showed early interstitial lung disease (ILD). Treatment and Outcome: The patient was managed with immunosuppressive therapy including mycophenolate mofetil and low-dose corticosteroids, showing stabilization of lung function and cutaneous symptoms over 6 months. Conclusion: This case highlights the importance of prompt diagnosis and early treatment initiation in systemic sclerosis to prevent irreversible organ damage.

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