World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
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ICV : 78.6

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Abstract

PANCHAKARMA: A CLASSICAL AND CONTEMPORARY INSIGHT INTO AYURVEDIC DETOXIFICATION AND REJUVENATION

Dr. Anuja Pandey* and Dr. Varij Pandey

ABSTRACT

Background: Panchakarma, the cornerstone of Shodhana Chikitsa (purification therapy) in Ayurveda, is a personalized detoxification and rejuvenation protocol designed according to Prakriti (constitution) and Dosha imbalance. Comprising Vamana (therapeutic emesis), Virechana (purgation), Basti (medicated enema), Nasya (nasal therapy), and Raktamokshana (bloodletting), it aims to eliminate Ama (toxins), restore Agni (digestive/metabolic fire), and enhance Ojas (vitality and immunity). Methods: A narrative review was conducted, synthesizing classical Ayurvedic texts (Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya, Bhavaprakasha) and contemporary biomedical studies focusing on clinical, biochemical, and physiological effects of Panchakarma. Relevant shlokas were included to establish textual authenticity. Results: Classical literature highlights the preventive, curative, and rejuvenative roles of Panchakarma. Charaka states: “????? ?? ??? ????????????? ???? ?????????? ????????” purification ensures optimal health. Modern research demonstrates significant reductions in oxidative stress, improved lipid and glucose metabolism, gut microbiota modulation, and neuroprotection, validating traditional concepts of Dosha balance and Agni-Ama theory. Conclusion: By integrating ancient Ayurvedic wisdom with contemporary evidence, Panchakarma emerges as a scientifically relevant, personalized protocol for detoxification, disease prevention, and management of lifestyle and chronic degenerative disorders.

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