Abstract

Gupta Sahil*

ABSTRACT

ABSTRACT Eosinophilic Esophagitis (EoE) is a chronic, allergen-induced, immune-mediated esophageal disorder characterized by esophageal eosinophilia (≥15 eos/hpf), food intolerance, and functional disturbances such as dysphagia and reflux. Modern interventions, including corticosteroids and dietary elimination, offer variable remission and carry long-term adverse risks. This case series presents a biopsy-confirmed pediatric EoE patient who is managed with individualized Ayurvedic protocols at IAFA®. The patient had a prior history of steroid dependence and persistent allergic symptoms. A comprehensive therapeutic approach focused on Agnideepana, Ama Pachana, Doshaa-specific Chikitsa, and Rasayana therapy, supported by Pathya-Apathya and Nasya procedures. Remarkable clinical improvements were observed, including symptomatic relief, histopathological recovery, and enhanced immune tolerance. Follow-up evaluations revealed sustained remission without corticosteroid use. These findings underscore the potential of Ayurvedic management as a viable, holistic alternative in chronic allergic esophageal disorders. Objective: To document and evaluate the outcomes of individualized Ayurvedic management of biopsy-confirmed EoE patients at the Institute of Applied Food Allergy (IAFA), focusing on symptom regression, immunological moderation, digestive correction, and overall quality of life. Methods: This case series examines a 10-year-old patient with EoE who underwent exclusive Ayurvedic management at IAFA. Clinical profiles were assessed using both modern diagnostic tools (endoscopy, biopsy, eosinophil counts, IgE levels) and Ayurvedic parameters (Dosha, Ama, Agnimandya, and Srotodusti). Treatment involved an Ayurvedic regimen comprising Ama-pacana, Agnideepana, Pitta-Kapha Shamana, and Rasayana therapies using herbal extracts, polyherbal formulations, medicated Ghee, and mucosal healers. Supportive Nasya, diet regulation (Pathya-Apathya), and Yoga-based breathing therapies were integrated to address systemic allergies, gut-immune dysfunction, and esophageal tissue repair. Results: The case study demonstrated significant clinical improvement within 8–12 weeks. Patient 1 (pediatric male) achieved complete remission of vomiting and dysphagia, normalization of eosinophil counts, and histological recovery (5 eos/hpf on follow-up).