World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

DRINKING AIR WITH MALSHE'S PIERCED STRAW CAN SATISFY HUNGER, INHIBIT GHRELIN AND MANEUVERING IT INTO THE INTESTINES CAN RELEASE GLP-1

Dr. Prakash Chintamani Malshe, MD*

ABSTRACT

The control of appetite and satiety involves complex gut-brain signaling mediated by hormones such as ghrelin and glucagon-like peptide-1 (GLP-1). Ghrelin, secreted predominantly by the empty stomach, stimulates hunger, while GLP-1, released in the intestines in response to nutrient contact, promotes satiety and insulin secretion. This hypothesis proposes a non-nutritive, mechanical method of influencing these hormonal signals using a novel tool: Malshe’s Pierced Straw.[1] The act of slowly drinking air through a pierced straw mimics the oropharyngeal and gastric mechanics of food intake without delivering calories, potentially downregulating ghrelin secretion. Further, if the ingested air is maneuvered into the intestines via specific yogic postures, it may stimulate mechanosensors and enteroendocrine L-cells to secrete GLP-1. This hypothesis opens a potential avenue for non-pharmacological appetite control and metabolic regulation through breath-manipulative techniques.

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