World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN (O) : 2455-3301
ISSN (P) : 3051-2557
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

CROHN'S DISEASE REVEALING DIFFUSE BRONCHIAL DILATIONS, A RARE EXTRADIGESTIVE MANIFESTATION: A CASE REPORT

Msika S., Belhaj C.*, Arfaoui H., Hallouli S., El Hanafy S., Bamha H., Bougteb N., Jabri H., El khattabi W. and Afif Mly H.

ABSTRACT

Inflammatory bowel diseases (IBD) are chronic and recurrent inflammatory disorders of the gastrointestinal tract, frequently associated with extraintestinal manifestations that can seriously affect the quality of life of patients with IBD. Respiratory involvement in IBD was first described by Lopez Botet and Rosalem Archer in 1962, and remains relatively rare. We reported the case of a 17-year-old female patient, followed for Crohn's disease for two years, receiving azathioprine and mercaptopurine, known to have suffered from chronic bronchorrhea for five years, and presenting with recurrent respiratory infections. The history of her illness began one week ago with the onset of moderately heavy hemoptysis accompanied by purulent bronchial syndrome, developing in a context of apyrexia and a decline in her general condition. Chest CT scan revealed bilateral and diffuse bronchial dilatation with mucoid impactions and diffuse bronchial thickening. Bronchial aspirates revealed the presence of Mycobacterium tuberculosis. The patient was started on antibacterial treatment according to the Moroccan national program, with good clinical progress and radiological clearance.

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