Abstract

Sreedevi A. P.*, Reeshma C.R., Sandhya V. R., Maneesha K.S., Anu Joy, Sibi Narayanan and Adithya Peethambara Panicker

ABSTRACT

Introduction: Digestosap, a polyherbal Ayurvedic syrup developed by Sitaram Ayurveda Pvt Ltd., is formulated to stimulate appetite and enhance digestive health. Given the increasing demand for safe and effective herbal remedies, rigorous quality assessment is essential to validate its therapeutic claims. This study employs a multifaceted analytical approach to evaluate Digestosap’s quality, safety, and efficacy. Materials & Methods: Digestosap was subjected to organoleptic evaluation for sensory attributes, physicochemical analysis for parameters like pH, specific gravity, total sugar, and phytochemical screening to identify bioactive compounds. Thin Layer Chromatography (TLC) was used to confirm key constituents, while microbial limit testing assessed safety. LC-MS analysis characterized the phytochemical profile responsible for its digestive benefits. Results & Discussion: Phytochemical analysis revealed flavonoids, phenols, glycosides, and alkaloids, supporting digestive and carminative effects. TLC verified constituents from ingredients like Dhanyakam and Pippali. Microbial testing showed no harmful pathogens and low counts (<10 cfu/ml). LC-MS identified compounds such as cinnamic acid, guaiacol, and stigmasterol, linked to gut health, anti-inflammatory, and metabolic benefits. Conclusion: Digestosap syrup demonstrates high quality, safety, and therapeutic potential as a digestive aid. Its diverse phytochemical profile, validated through LC-MS, supports its efficacy in enhancing appetite and digestion. This study bridges traditional Ayurvedic knowledge with modern analytical science, establishing Digestosap as a promising herbal formulation for clinical use in digestive health management.