World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
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ICV : 78.6

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Abstract

CLINICAL STUDY TO ASSESS THE SAFETY AND EFFICACY OF NISHA AMALAKI YOGA WITH AND WITHOUT HONEY IN PATIENTS OF PRAMEHA W.S.R. TO PRE- DIABETES

Dr. Prachisha P.C.*, Dr. Sumit Nathani and Mr. Gaurav Sharma

ABSTRACT

Introduction: According to Ayurveda classics, Prameha is a syndrome and 20 different types of it is explicated with a common characteristic of copious flow of cloudy or turbid urine frequently. The etiological factors, pathogenesis, signs and symptoms of Prameha resemble very closely with that of Prediabetes. Prediabetes is the stage before Diabetes in which impaired fasting glucose levels are observed. This stage is the vital period for preventing type II diabetes as it can be reversed and cured completely. The aim of this study is to evaluate the safety and efficacy of Madhu as anupana in the management of Prameha (Prediabetes) and to revalidate the efficacy and safety of Nisha Amalaki yoga in the management of Prameha (Prediabetes). Material and Methods: 30 patients were enrolled in this clinical trial and were randomly divided into two groups – Group-A and Group-B with 15 patients in each. The Nisha Amalaki yoga choorna was administered in a dose of 8 g daily in 2 divided doses before meals with luke warm water as anupana in Group A and 10 gm (7ml) Madhu in Group B for 30 days. The patients were followed up every 15 days for one month and the assessments were done. The results of the subjective data were statistically assessed with „Wilcoxon paired rank test? and that of objective data with paired „t? test. Results: Significant results were observed in subjective parameters like prabhutamutrata, avilmutrata, trishnadhikya, kshudhadhikya, swedadhikya, karpadadaha, karapadasuptata, and daurbalya and objective parameters like FBS and lipid profile of both the groups. Conclusion: The study confirms that Nisha Amalaki yoga with and without honey were equally effective in treatment of Prameha by reducing majority of the symptoms.

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