IGA NEPHROPATHY WITH THROMBOTIC MICROANGIOPATHY - CASE SERIES FROM A TERTIARY CARE CENTRE IN SOUTH INDIA
Dr. Nayana Babu*, Dr. Manjusha Yadla, Dr. Vikram B., Dr. Srikanth and Dr. Sreenivas
ABSTRACT
While Immunoglobulin A(IgA) nephropathy(IgAN) with Thrombotic microangiopathy (TMA) is often documented in biopsy reports, its impact in disease progression requires more research. Here we studied a case series of 10 patients of biopsy proven IgAN with TMA to analyse the clinical ,laboratory with serological data and their outcome. Mean age was 32± 5 years and no gender specific differences. All presented with uncontrolled blood pressures, renal failure and were dependent on dialysis and had high mortality. There were no evidence of TMA in blood investigations. Hence this study concludes that IgAN with TMA is associated with worse renal prognosis.
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