Abstract

Sameera Begum, Akshaya Reddy Palla, Arepalli Pooja and Tajuddin Shaik*

ABSTRACT

Background: Boerhavia elegans leaves extract contains alkaloids, tannins, saponins, triterpenoids, flavonoids, volatile oils, phenolic and glycosides. Pharmacological screening provided more proof of its antioxidant and antihyperlipidemic properties. The antioxidant and antihyperlipidemic capacity are evaluated using DPPH and Nitric oxide scavenging activity. The HMG COA reductase enzyme blocks the conversion of HMG COA and NADPH. This interference in the biosynthesis pathway results in lower cholesterol levels. Meanwhile, both the aqueous and ethanolic extracts off Boerhavia elegans have been found to exhibit anti hyperlipidemic effects, helping reduce elevated lipid levels in the body. Objective: To evaluate in vitro both anti-oxidant and lipid-reducing properties of Boerhavia elegans. To carry out the preliminary screening, statistical studies, antioxidant and Antihyperlipidemic effectiveness of the leaf extract of plant Boerhavia elegans. Materials and Procedures: The leaf extract of Boerhavia elegans contains multiple components such as alkaloids, tannins, saponins, triterpenoids, flavanoids, volatile oils, phenolic substances, and glycosides. To investigate its antioxidant capabilities, tests involve the DPPH and nitric oxide scavenging methods. Furthermore the anti cholesterol potential is examined through HMGCR inhibition assays. Results: After that pharmacological screening of Antihyperlipidemic studies, the effect of Boerhavia elegans is HMGR levels was considerably lowered to almost normal by taking atorvastatin.