Abstract

Jyoti Dhondiram Kshirsagar*, Asha Anil Lakariya, Sadik Mansoor Khan and Sachin Ramkrishna Patil

ABSTRACT

Background: Chronic heart failure is a prevalent clinical syndrome and a major global health concern. Sampurna Hruyday Shudhikaran (SHS) therapy, is a combination of Panchakarma and allied therapies. This observational study aimed to explore its efficacy in improving ejection fraction in cardiac patients. Methods: A retrospective, single-centre, observational, investigator-initiated study was conducted at Madhavbaug Clinic in Maharashtra from February 2022 to July 2024. Inclusion criteria were patients diagnosed with ischemic heart disease, chronic heart failure, and dilated cardiac myopathy with ≤50% ejection fraction. Exclusion criteria were acute myocardial infarction, heart block, and pacemaker implantation. Follow-up was conducted at 30, 60, and 90 days. Baseline and follow-up data were compared. Results: This study included 15 patients (mean age: 62.53 ± 9.80 years). Mean ejection fraction increased from 35.13 ± 10.61% to 42.20 ± 13.53% at the 90-day follow-up. Significant improvements were observed in VO2max (day 1: 12.86 ± 2.08 mL/kg/min; day 30: 16.62 ± 1.59 mL/kg/min; day 60: 19.45 ± 1.80 mL/kg/min; day 90: 21.59 ± 2.04 mL/kg/min) and metabolic equivalent (MET) value (day 1: 3.69 ± 0.59; day 30: 4.75 ± 0.45; day 60: 5.56 ± 0.51; day 90: 6.17 ± 0.48). Additionally, the 6-minute walk test showed marked improvement, increasing from 288.67 ± 68.40 m on day 1 to 581.43 ± 60.26 m on day 90. Conclusion: The integration of Ayurvedic Panchakarma therapy with allopathic medication has proven effective in improving ejection fraction and key cardiac risk factors such as VO?max while reducing patients' dependence on allopathic medications.