BIOACTIVE POTENTIAL OF CATECHIN AND EPICATECHIN FROM ACACIA CATECHU WILD. A PHARMACOLOGICAL APPROACH
Harshit Mishra, Ankur Kapil*, Manoj Sharma, Ankit Singh Tomar, Yogesh Yadav and Sanskar Bhardwaj
ABSTRACT
Catechin and epicatechin are natural compounds found in the heartwood of Acacia catechu; a plant Extensively used in traditional medicine. These compounds possess several beneficial pharmacological activities, including antioxidan, antimicrobial, anti-inflammatory and anticancer effects. As antioxidants, catechin and epicatechin safeguard cells from harm caused by potentially damaging molecules known as free radicals. This makes them valuable in preventing diseases linked to oxidative stress, such as heart disease and diabetes. Their anti-inflammatory properties result from their ability to reduce substances in the body that cause swelling and pain, which could help manage conditions such as arthritis. These compounds also show strong activity against bacteria and fungi, making them useful in treating infections. Moreover, catechin and epicatechin have been studied for their ability to fight cancer by stopping the growth of cancer cells and triggering their destruction. This review highlights the multiple health benefits of catechin and epicatechin and their potential as natural treatments for various diseases. Additional research is required to gain a clearer understanding how they work and to develop methods that enhance their effectiveness for medical use.
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