MELOXICAM-EXCIPIENT COMPATIBILITY STUDIES FOR ADVANCED DRUG DELIVERY SYSTEMS DEVELOPMENT
Mokhtar Abd-hafiz Al-Ghorafi, Mahmoud Mahyoob Alburyhi*, Maged Alwan Noman, Abdalwali Ahmed Saif
ABSTRACT
Meloxicam emulgels are a topical formulation that contains the non-steroidal anti-inflammatory drug (NSAID) Meloxicam. It is used for the treatment of pain and inflammation associated with conditions such as osteoarthritis and rheumatoid arthritis Emulgels are the result of combining the terms emulsion and gel. It has a number of features, including enhanced permeability and strong thermodynamic stability. These are either water in oil emulsion or oil in water emulsion, by combining it with a gelling agent, it became gelled Emulgels offers a dual control and a long-lasting release and patient compliance. It was concluded that the drug Meloxicam was found to be compatible with various excipients which were selected for the formulation development of the Meloxicam Emulgels. Formulation scientist from his experience and knowledge have to significantly in the preformulation study stage and is an important factor in the ADDS (Advanced Drug Delivery Systems) product development process.
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