Abstract

Krishna Mohan Chinnala and Mayuri Konda*

ABSTRACT

Smoking is injurious to health. Smoking termination (quit smoking) is the process of discontinuing smoking. Tobacco consists of nicotine, which is addictive and causes pulmonary diseases. Nicotine makes the process of quitting very prolonged and complex. Smoking is the foremost unnecessary basis of demise worldwide, and quitting smoking drastically reduces the risk of dying from tobacco-related diseases such as heart disease and lung cancer. The current established procedures for smoking cessation embrace wide variety of side effects, but as a comparison sublingual or buccal thin films are a better alternative due to negligible side effects and fast discharge of nicotine which also avoids first pass metabolism. Thin-film drug release has established as a better substitute to the conventional tablets, capsules and liquids dosage forms. Thin films are similar in size, outline and thickness to a postal stamp, thin-film strips are classically designed for oral route of administration, with the user placing the strip on or under the tongue (sublingual) or along side of the cheek (buccal). Utilization of oral films has attracted momentous consideration in therapeutic and nutraceutical applications. The current study is focusing usage of nicotine buccal thin films for the release of nicotine to aid in smoking cessation.