A REVIEW ON DIFFERENT FIVE MEMBERED NITROGENATED HETEROCYCLIC COMPOUNDS AND THEIR PHARMACEUTICAL ACTIVITIES
*Aanand L. Deshmukh, Rasika R. Raut, Gajanan M. Jawalkar and Harigopal S. Sawarkar
ABSTRACT
Five-membered nitrogenated heterocyclic compounds constitute a significant class of molecules with widespread applications in the pharmaceutical industry. This review briefly examines several key examples, including pyrroles, pyrazoles, imidazoles, and triazoles, highlighting their diverse pharmacological activities. These heterocycles serve as core structures in numerous drugs and drug candidates exhibiting anti-inflammatory, anti-cancer, anti-fungal, anti-viral, anti-hypertensive, and anti-ulcer properties, among others. The structural versatility of these scaffolds allows for the design and development of novel therapeutic agents targeting a broad range of diseases. While this overview provides a general introduction, the specific pharmacological profile of each compound is highly dependent on its substituents and overall molecular architecture.
[Full Text Article] [Download Certificate]