Abstract

Dr. Nidhi Sharma* and Dr. Anil Kumar Sharma

ABSTRACT

A 13 year old male child came at R.G.G.P.G. Ayurvedic college and Hospital Paprola with pain and idiopathic swelling over thigh region with no history of any trauma which was noted incidentally by him 4 days back. There was no history of any kind of trauma and fall. On clinical examination there was massive swelling on left thigh and the local temperature was raised. Patient also had fever 20 days back. After radiological evaluation, in which periosteal reaction was seen and CT left thigh, which was suggestive of osteomyelitis mid shaft femur the provisional diagnosis was made as osteomyelitis left femur. But after further workup and higher investigations the diagnosis was changed and the final diagnosis was concluded as Ewing’s sarcoma. Ewing’s sarcoma is an aggressive sarcoma of bone and soft tissue. It is considered a prime example of paradigms of translocation positive sarcoma genetically rather simple disease with a specific and neomorphic potential therapeutic target.[1] The treatment of Ewing’s sarcoma relies on multidisciplinary approach, coupling intensive neoadjuvant and adjuvant chemotherapies with surgery or radiotherapy for control of primary site and possible metastatic disease. Current 5- year overall survival for patients with localized disease is 65-75%. Patients with metastasis have a 5-year overall survival <30%, except for those with isolated pulmonary metastasis approximately 50%.[2] So, before concluding the final diagnosis, higher clinical investigations should be done in case of suspicion, to prevent the diagnostic errors which may result in devastating consequences.