World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

NEONATAL JAUNDICE: A COMPREHENSIVE REVIEW OF ETIOLOGIES, CLINICAL MANIFESTATIONS, AND MANAGEMENT STRATEGIES

Attia Imdad* and Ume Amara

ABSTRACT

Neonatal jaundice, characterized by the yellowish discoloration of the eyes and skin in newborns due to elevated bilirubin levels, poses a significant health concern worldwide. This review article aims to provide a comprehensive overview of neonatal jaundice, including its diverse etiologies, clinical presentations, and management approaches. The discussion encompasses both physiological and pathological causes, highlighting key factors influencing the need for treatment, such as bilirubin levels, age of the infant, and underlying conditions. Moreover, the review explores associated clinical features, such as excess sleepiness and loss of appetite, as well as potential consequences such as seizures and cerebral palsy. Various management strategies, ranging from conservative measures like frequent feeding to more advanced interventions like phototherapy and exchange transfusions, are examined in detail. Through synthesizing current knowledge and evidence-based practices, this review aims to enhance understanding and optimize management approaches for neonatal jaundice, ultimately contributing to improved outcomes for affected infants.

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