Abstract

Nada Omer Alseedig*, Raian Bakhet Yassein, Siham Khalifa Abd Allah, Areeg Alsail Mohmmed, Nosiba Abdelmajid Alballah, Mohamed Abedelrahman Syid

ABSTRACT

Renal disease is a common cause of death and disability in Sudanese patients. Chronic kidney disease (CKD) is a common threat to critically ill patients in intensive care units with a mortality rate ranging from 42% to 88%. Treatment methods such as dialysis and transplantation are becoming more effective in life threatening conditions. This study was conducted to assess the coagulation profile level in chronic kidney failure patients and comparison was made with age matched controls. Totally one hundred members were selected for the study, fifty members were chronic kidney failure patients and fifty members were normal healthy subjects served as controls. The results of this study showed that mean of Prothrombin time (PT) and international normalization ration (INR) were exhibited significant increased which decreased significantly depend on the duration of disease. From our study we concluded that presence of variation in coagulation profile among Sudanese chronic kidney failure patients when compare with control. Coagulation profile affects the circulatory system which progress many health hazards. Coagulation profiles give information about status and clinical course of disease. Regular monitoring of coagulation profile in CKF patients improves the quality of life.