Abstract

Mohan Tabade*, Priyanka Zendekar, Shubhangi Manikpuriya and Dr. Gajanan Sanap

ABSTRACT

Transdermal drug delivery systems, or TDDSs, are adhesive patches applied to the skin with a precise dosage that are then absorbed into the bloodstream. It is important to take into account the entire morphological, biophysical, and physicochemical aspects of the skin when delivering medicinal substances through the human skin for systemic effects. A transdermal patch offers a regulated release and continuous drug administration, which is advantageous over other forms of pharmaceutical delivery. It also avoids pulsed entry into the systemic circulation, which frequently results in undesirable side effects. Transdermal patches are among the most significant new drug delivery systems; they are a painless method for. For a research scientist interested in TDDS, the TDDS review article offers a convenient source of information about TDDS and its evaluation method. Transdermal drug delivery systems (TDDS), sometimes referred to as "patches," are dosage forms intended to distribute a medication dosage that is therapeutically efficacious through a patient's skin. To administer therapeutic drugs for systemic effects via the human skin, it is necessary to take into account the skin's complete morphological, biophysical, and physicochemical features. Transdermal administration offers a significant advantage over oral and injectable methods due to its ability to prevent first pass metabolism and increase patient compliance, respectively. In addition to enabling continuous distribution of medications with brief biological half-lives, transdermal delivery also prevents pulsed entrance into systemic circulation, which frequently results in undesired side effects.  The transdermal drug delivery systems and its evaluation process specifics are detailed in the TDDS review articles, which are a useful resource for research scientists working on TDDS.