World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

ASSESSMENT OF THE ANTI-INFLAMMATORY EFFECT OF DASHANG LEPA IN ACUTE EXPERIMENTAL MODELS IN ALBINO RATS

Dr. Kumar Ravindra*, Dr. Gupta S. J. and Dr. Trigunayat Anshuman

ABSTRACT

Background/Purpose: Inflammatory swellings such as – cellulitis, erysipelas, boil, carbuncle etc. are major issue in health sciences. Inflammatory swellings are a part of body?s inflammatory process, which helps the body when it becomes injured. Our body undergoes the inflammatory process virtually any time an injury or tissue damage occurs. Along with redness, heat and pain, swelling is a sign of the inflammatory process at work. The principle of management of inflammatory swelling is to localize the infection avoid the toxic substance/bacterial growth, to go in systemic circulation. To study the anti-inflammatory effect of Dashang Lepa in acute, experimental models in albino rats. Methods: Dashang Lepa contains 10 commonly and easily available and very cost affective indigenous drug which all having good effect in reducing the Vranashopha. Anti- inflammatory effect of Dashang Lepa was studied in carrageenin-induced hind paw oedema in rats and the paw volume was measured plethysmometrically at 5 hour after injection. All the drugs were applied locally. Results: The paw volume was significantly reduced in standard (mean = 0.86, p

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