World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF HIBISCUS SABDARIFFA PETALS

Sujata Anil Salve*, Dr. G. V. Bihani and Dr. K. R. Biyani

ABSTRACT

This study aimed at Hepatoprotective Activity of Hibiscus Sabdariffa Petals was evaluation in alcohol induced Liver Necrosis in rats. The Hepatoprotective Activity of aqueous extract of petals of Hibiscus Sabdariffa was evaluated at different dosage of 100 mg/kg and 200 mg/kg. Administration of this extract showed significantly decreased serum levels of AST, ALT, ALP, and bilirubin in a dose-dependent manner. These are indications of Hepatoprotective Activity of aqueous extract of petals of Hibiscus Sabdariffa proving hepatoprotective Activity by comparing favorably well with Silymarin, a standard hepatoprotective drug. The aqueous extract of petals of Hibiscus Sabdariffa restored liver function and hematological parameters to normal control levels against hepatic damage induced by ethanol.

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