World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

GAYET WERNICKE'S ENCEPHALOPATHY AND PREGNANCY: ABOUT 3 CASES AND REVIEW OF THE LITERATURE.

*Imane Laghrich, Soukaina Laaraj, Khalid Guelzim, Abdellah Babahabib and Jaouad Kouach

ABSTRACT

Gayet Wernicke's encephalopathy (GWE) is a neuropsychiatric syndrome of metabolic origin deficiency secondary to a profound deficiency of thiamine (vitamin B1). GWE is mostly seen in alcoholics, but can also appear in case of malnutrition. In obstetrics, GWE is the result of hyperemesis gravidarum because of low thiamine, as well as increased thiamine requirements. It is difficult to diagnose and whose course in the absence of treatment leads to severe cognitive sequelae. Magnetic resonance imaging is the gold standard for confirming the diagnosis by the presence of hyper T2 signals in the periaqueductal, thalami, and mammary bodies. This work aims to analyze the diagnostic management and therapeutic management in pregnant women with Gayet-Wernicke encephalopathy, who have been hospitalized in the Gynecology-Obstetrics department of the Mohamed V Military Hospital of Instruction -Rabat.

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