World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
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Abstract

PHARAMACEUTICAL STUDY OF TAMRESHWAR RASA KUPIPAKWA RASAYAN

Dr. Yogesh Dilip Madgulwar*, Dr. Tushar More and Dr. Radhika Katarmal

ABSTRACT

Rasashastra is also a actually ancient text and it's the result of further than thousand times of research. In traditional system of medicine, the use of Rasashastra and Rasaushadhi are the revolutionary development. generally, Rasashastra deals in metallic and herbo mineral drugs with colored kalpanas including Kupipakwa Rasayana. While Rasaushadhi are mentioned in various rasa texts in terms of their effectiveness and it's in practice since ancient times Rasaushadhi are very effective in many aspects like long lasting effects, simple palatability, rapid onset of action, small dose and having better efficacy to cure the complex diseases (Asadhya vyadhis). There is no needing of evaluation of patient testing, desh, kal and dosha with the utilization of rasaushadhi. Kupipakwa Rasayana Kalpana is additionally referred to as Sindhura Kalpana. It is made from four words that's kupi- glass bottle, pakwa- heating or paka, rasa- parada, aayana- sthan. Kupipakwa method is a special procedure in which kajjali main ingredients. The role of temperature is very important to get the desired and beneficial effect in the final product Many observations and precautions are involved within the process of Kupipakwa Rasayana. In this, mercury (Hg) known as parada has been widely used and other drug is sulphur known as Gandhaka has been also used frequently. There are several chemical changes are seen within the finished product. Now a day, with Parada and Gandhaka there are chemical reactivity are well known. Objective: Preparation of Tamraeshwar Rasa as per classical reference.[1] Materials and Methods: The Kajjali(fine black lustreless powder) of Tamreshwar Rasa in Kacha Kupi (glass bottle) was given heat with Kramagni (graded heat pattern) in EMF for 36hrs.Melting of Kajjali( Black lustreless mercurial compound) was observed at around 260 ?C, whereas the flame started at 357 ?C. Maximum temperature required for production was 650 ?C. Final yield of 32% was observed in preparation of Tamreshwar Rasa. Conclusion: Tamreshwar Rasa is Sagandha, Bahirdhuma, Kantastha Kupipakwa[12] Rasayana(Sublimated compound formed in glass bottle). It are often prepared in 36 hours following classical guidelines.

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