EMULGEL: A NOVEL TREND IN TOPICAL DRUG DELIVERY SYSTEM
Johnsey Joseph, Daisy P.A.*, Boby Johns George, Praveen Raj R, Noby Thomas and Betty Carla
ABSTRACT
For the treatment of local as well as systemic skin disorders, topical drug delivery systems have been used for centuries offering the advantage of delivering the drug directly to the site of action and also delivering the drug for extended period of time at the affected area. When gel and emulsion are used in combined form the dosage form are referred as Emulgel. Since they contain dual control release systems: a gel and an emulsion, emulgels have emerged as one of the most interesting topical delivery system. They are emulsions of either oil-in-water or water in oil type, which are gelled by mixing with a gelling agent. The major objective behind emulgel is delivery of hydrophobic drugs via skin. Thus emulgels have major advantages on novel vesicular system as well as on conventional systems in various aspects. They are referred for topical use due to their favorable properties such as being greaseless, non-staining, thixotropic, emollient, easily removable, water soluble, bio-friendly, long shelf-life, transparent and pleasant appearance. The use of emulgels can be expanded in different classification namely analgesics, anti-inflammatory, anti-fungal, antiacne drugs and various cosmetic formulations.
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