World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

ROLE OF KASISADI GHRITA IN PARIKARTIKA (FISSURE-IN-ANO)

Devkinandan Wagh*, Seema Dhabaliya, Pravinkumar Kharadi and Jasmin Gohel

ABSTRACT

Fissure in ano is a troubling and painfulcondition that affects a great majority of the population the world over. Chronic anal fissures are associated with persistenthypertonia and spasm of the internal anal sphincter and they have conventionally been treated surgically. However, concerns have been raised aboutthe risk of faecal incontinence after surgical sphicterotomy. Ancient text could not give a brief idea about this condition. Mainly it is described as complicationof Basti karma and Atisar. Present management of fissure isto give some laxatives, local anaesthetic agent, antibiotics and analgesics. If this treatment fails, then patient isrecommended for surgical procedure but it alsoleaves many problems after operation. Inthis study Kasisadi ghrita wasselected which is having effective Vrana shodhana and Vranaropan properties. Also, the drugs in the Ghrita medium give good lubricating action relieving muscular spasm. A total 15 patientshaving signs and symptoms of Parikartika (Fissurein ano) were selected and Kasisadighritha was given in the dose of 10 ml intra- rectally once a day for 15 days. Patients were assessed onparameters such as Pain, Bleeding per rectum, Itching and BurningSensation. The Significant relief was observed in sign and symptoms after treatment andit was concluded that Kasisadi Ghrita as an effectiveand a safe alternative method to surgicaltreatment.

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