QUALITY BY DESIGN (QbD) APPROACH FOR THE MODIFICATION OF POORLY SOLUBLE DRUGS
Mehta Dhirendra Kumar*, Kachawa Vijay Singh, Sharma Ranu, Garg Ayush, Kumar Dileep and Dr. Dwivedi Jayesh
ABSTRACT
The current work aims to modification of poor soluble drugs by QBD approach. Quality by design (QbD) encourages the pharmaceutical industry to use risk management and science-based manufacturing principles to gain process and product understanding and thus assures quality of the product. Physiochemical properties and 32factor are analysis in this study. FTIR, DSC thermogram etc are also done. Ranolazine and olmesartanmedoxomil with different polymers are used.
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