World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

PHARMACOGNOSTIC, PHYTOCHEMICAL, AND PHARMACOLOGICAL INVESTIGATION ON BARK OF THUJA ORIENTALIS LINN (CUPRESSACEAE)

Malode Sunanda*, Bodile Shubhangi, Niranjan Bhadakwade, Omkar Shikare, More Akshaya and Malode Manisha

ABSTRACT

The present research was conducted to investigate the analgesic activity of Ethyl acetate soluble alcoholic (ETA) extracts of plants of Thuja orientalis. (Family: Cupressaceae) The analgesic activity of the ethyl acetate soluble alcoholic extracts of the Thuja orientalis at the dose of 100mg/kg body weight was evaluated against the standard drug – Pentazocineat a dose of 10 mg/kg body weight. Adult swiss albino mice of either sex of six numbers in each group, was undertaken for study and evaluated by Hot Plate Method and Tail Immersion Test. The Ethyl acetate soluble alcoholic extracts of plants of Thuja orientalis showed greater analgesic activity when compare with the standard drug. Result of present studies suggest that ETA extract of Thuja orientalis significant (P value < 0.001) analgesic activity.

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